Will clients need anything to run my EXEs?

[tom64]

If I make a program that uses SFML is there any chance it won't run because they don't have something installed? i.e. They won't need .NET, or OpenGL, etc.?

[AlexxanderX]

For .NET cases I don't know, but maybe some dlls and everything app use( images, etc...).

[eXpl0it3r]

This all depends on the platform you're talking about and how you link the dependencies.
So you should provide more information.

If you use C++ & SFML there's no need for the .NET framework.

[tom64]

I'm using Visual Studio to write C++. I'm not really sure what .NET is, all I know is I don't want it. I'm not sure if VS automatically adds it to C++ exes or not.

[Laurent]

I'm not really sure what .NET is

Something you don't have to care about if you do C++. It's a language family (C#, Visual Basic.Net, ASP.Net, ...) with its big framework.